Prurigo Nodularis Treatment

at Mosaic Dermatology in West Fargo

Prurigo nodularis is a chronic skin condition that causes intensely itchy, raised bumps (nodules) on the skin. The condition can significantly impact a person’s quality of life due to persistent itching and discomfort. While the exact cause is unknown, various effective treatments are available to manage symptoms and improve skin health. At Mosaic Dermatology, we specialize in the diagnosis and treatment of prurigo nodularis with individualized care plans designed to reduce itching and restore skin integrity.

What Is Prurigo Nodularis?

Prurigo nodularis is characterized by firm, itchy nodules that can appear anywhere on the body, commonly on the arms, legs, and trunk. The persistent urge to scratch leads to skin thickening and further irritation. Over time, this cycle of itching and scratching worsens the condition, making early diagnosis and proper management essential.

Causes and Risk Factors for Prurigo Nodularis

While the precise cause of prurigo nodularis is unknown, several factors are associated with its development:

  • Chronic itching: From conditions such as eczema or psoriasis.
  • Nerve-related causes: Conditions affecting the nervous system may contribute to persistent itching.
  • Underlying health issues: Including liver disease, kidney disease, thyroid disorders, and HIV.
  • Allergic reactions: Certain allergens or irritants may exacerbate symptoms.
  • Mental health conditions: Anxiety and depression can contribute to the itch-scratch cycle.

Symptoms of Prurigo Nodularis

  • Multiple, firm, raised bumps (nodules) on the skin.
  • Intense itching that may worsen at night.
  • Thickened, scaly, or rough skin due to repeated scratching.
  • Open sores or scabs from continuous scratching.
  • Hyperpigmentation or hypopigmentation (darkening or lightening of the skin) in affected areas.
  • Scarring in chronic cases.

Prurigo Nodularis Treatment Options

At Mosaic Dermatology, we provide comprehensive treatment plans tailored to each patient’s specific needs and the severity of their condition:

Topical Treatments
  • Corticosteroid creams or ointments: To reduce inflammation and itching.
  • Topical calcineurin inhibitors: Such as tacrolimus or pimecrolimus for sensitive areas.
  • Capsaicin cream: Helps decrease the itching sensation by affecting nerve fibers.
Phototherapy (Light Treatment)
  • Narrowband UVB therapy: Exposure to specific wavelengths of ultraviolet light to reduce inflammation and itching.
Systemic Treatments
  • Oral antihistamines: To control itching, especially at night.
  • Immunosuppressive medications: Such as methotrexate or cyclosporine for severe cases.
  • Neuromodulating medications: Such as gabapentin or pregabalin, which address nerve-related itch pathways.
  • Biologic therapies: Targeted medications such as dupilumab or nemolizumab that help control immune responses associated with prurigo nodularis.

Managing and Preventing Prurigo Nodularis Flare-Ups

  • Moisturize regularly: To maintain skin hydration and prevent dryness.
  • Identify and avoid triggers: Such as allergens or irritating fabrics.
  • Use gentle skincare products: Fragrance-free and hypoallergenic options are recommended.
  • Practice stress-reduction techniques: Such as meditation, yoga, or counseling.
  • Keep fingernails trimmed: To minimize skin damage from scratching.

When to See a Dermatologist

You should seek professional care if you:

  • Experience persistent itching that does not respond to over-the-counter treatments.
  • Notice the development of multiple raised nodules on your skin.
  • Have open sores or infections from scratching.
  • Experience sleep disturbances or emotional distress due to itching.

Expert Prurigo Nodularis Care in West Fargo

At Mosaic Dermatology, we are committed to providing expert care for prurigo nodularis through advanced diagnostic techniques and personalized treatment options. Our goal is to help you manage symptoms, restore healthy skin, and improve your quality of life. Schedule an appointment today for effective prurigo nodularis management and relief from itching.